Not that I'm working on a MMORPG, but I have been thinking about something similar lately...
Imagine World of Warcraft with a Diablo-esque perspective. How would you control it?
Questions to answer:
Consider standard 3D MMORPG control. Is the WASD combination out of the question, since a fixed perspective doesn't really lend itself well to simple directions?
Or would WASD still be a legitimate method of control?
Now, imagine that the keyboard can't be used for movement at all - perhaps it is completely occupied with other tasks, like managing communication...
How would you use the mouse? Imagine you have only two mouse buttons. Would you left-click to move, right-click to select things and talk to npcs?
Or would you prefer something like an RTS's context-sensitive right-clicks: right-click to move, left-click to target, right-click to attack/talk?
AoDC, would you like to chime in? What is your control scheme for OoL?
I'd love to hear what everyone has to say. I'm not here to debate, I'm here to listen. All ideas are welcome. =)