I'll admit it. I'm a manga guy. If you look in my collection you'll see about 100 tankoban in it, and yet American comic from only three or four series. Every couple of months I try getting into American comics, but, I have trouble. I hate Superheroes, and they make up most of what you see at an American comic store. The only exception would be Batman, I guess. Otherwise they can all blow me. The other series that I might like I usually don't discover until after they made a movie out of it (V for Vendetta, 300, Wanted) or something, and they usually last about 5 minutes before they vanish into thin air, while Superhero comics last decades and gut dozens of spinoffs.
So please, give me a current American comic that is less than a trillion years old and has nothing to do with Superness.